Single molecule force spectroscopy unravels the complex dynamics of HSP70-induced protein conformation

A new way to study protein modifications and the associated chaperones that protect the protein from non-cognate interactions could help us understand what actually drives the modifications. Such an understanding could help explain the progression of diseases such as cancer, Parkinson's and Alzheimer's. Proteins are involved in almost every process in a cell. This requires them to adopt a precisely defined 3-D structure to carry out their specified function, called 'conformational conformation'. But during this time, a variety of conditions such as chemical, environmental and physical stress can cause protein…

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Indian researchers have identified four different types of ILs that could prove effective in extracting silk proteins from raw fibres

Researchers have found an environmentally friendly approach that could eliminate the use of toxic chemicals in silk processing. Traditionally, toxic chemicals such as sodium carbonate, sodium hydroxide, sulfuric acid and lithium bromide are used to extract silk proteins, fibroin and sericin from various types of raw silk fibres, which is a crucial part of the process of making silk from cocoons. A team from the Institute of Advanced Study in Science and Technology (IASST) Guwahati, an autonomous institute of the Department of Science and Technology, has identified ionic liquids (ILs)…

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Six-lane controlled access road project in Mopa dedicated to the nation

Enhancing modern road connectivity in Goa, Union Minister for Road Transport and Highways Shri Nitin Gadkari today dedicated to the nation the 6-lane access-controlled road with elevated viaducts from Manohar International Airport to Dhargal on NH-166S in Goa. The 7 km long project costing ₹1183 crore will significantly improve connectivity to Manohar International Airport, facilitating faster and hassle-free travel. The development is expected to boost tourism activities and promote multi-modal connectivity, thereby reducing logistics costs. Additionally, it aims to make traffic more smooth and safer, thereby saving on fuel consumption…

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